Alfacort Hydrocortisone 1% Cream is generally used to manage and relieve the symptoms of mild inflammatory skin conditions. Skin Irritations: It can help soothe itching, redness, and inflammation caused by various irritants, such as insect bites, rashes, or contact dermatitis. Eczema (Atopic Dermatitis): Mild hydrocortisone creams like Alfacort can provide relief from itching and mild inflammation associated with eczema flare-ups.